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Ingredients: 100% pure anamu whole herb (Petiveria alliacea). This product is non-irradiated and non-fumigated. It is a wild harvested product—grown naturally in the Brazilian Amazon without any pesticides or fertilizers.
Suggested Use: As a nutritional supplement, take 2-3 capsules twice daily or as directed by a health care professional.
Contraindications: Methanol extracts of anamu were reported to cause uterine contractions, therefore, it is contraindicated in pregnancy.
Drug Interactions: None published. Due to anamu’s natural coumarin content, however, it is conceivable that it might potentiate the effects of coumadin.
Other Practitioner Observations:
- Anamu contains a low concentration of coumarin, which has a blood thinning effect. People with blood disorders, such as hemophilia, should be monitored closely for this possible effect
- This plant has been shown to have hypoglycemic effects. People with hypoglycemia should be monitored more closely for this possible effect.
- Graviola Max, a proprietary blend of Annona muricata and Annona montana
- A-F, a proprietary blend of Rainforest botanicals traditionally used by Shamans against fungi and Candida infections
- Colloidal Silver, the ancestor of modern antibiotics
References on Anamu
Cytotoxic & Anticancerous Actions:
An, H., et al. "Synthesis and anti-tumor evaluation of new trisulfide derivatives." Bioorg. Med. Chem. Lett. 2006 Sep; 16(18): 4826-9.
Williams, L. A., et al. "In vitro anti-proliferation/cytotoxic activity of sixty natural products on the human SH-SY5Y neuroblastoma cells with specific reference to dibenzyl trisulphide." West Indian Med. J. 2004 Sep; 53(4): 208-19.
Ruffa, M. J., et al. “Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma cell line.” J. Ethnopharmacol. 2002; 79(3): 335-39.
Mata-Greenwood, E., et al. “Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells.” Anticancer Res. 2001; 21(3B): 1763-70.
Rosner, H., et al. “Disassembly of microtubules and inhibition of neurite outgrowth, neuroblastoma cell proliferation, and MAP kinase tyrosine dephosphorylation by dibenzyl trisulphide.” Biochem. Biophys. Acta 2001;1540(2): 166-77.
Jovicevic, L., et al. “In vitro antiproliferative activity of Petiveria alliacea L. on several tumor cell lines.” Pharmacol. Res. 1993; 27(1): 105-06.
Rossi, V., et al. “Antiproliferative effects of Petiveria alliacea on several tumor cell lines.” Pharmacol. Res. Suppl. 1990; 22(2): 434.
Yan, R., et al. “Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemaglutinin-activated Jurkat cells.” Pharmacol. Res. 2001; 44(2): 135-39.
Weber, U. S., et al. “Antitumor activities of coumarin, 7-hydroxy-coumarin and its glucuronide in several human tumor cell lines”. Res. Commun. Mol. Pathol. Pharmacol. 1998; 99(2): 193-206.
Bassi, A. M., et al. “Comparative evaluation of cytotoxicity and metabolism of four aldehydes in two hepatoma cell lines.” Drug Chem. Toxicol. 1997 Aug; 20(3): 173-87.
Immunostimulant Actions:
Queiroz, M. L., et al. “Cytokine profile and natural killer cell activity in Listeria monocytogenes infected mice treated orally with Petiveria alliacea extract. Immunopharmacol. Immunotoxicol. 2000 Aug; 22(3): 501-18.
Quadros, M. R., et al. “Petiveria alliacea L. extract protects mice against Listeria monocytogenes infection—effects on bone marrow progenitor cells.” Immunopharmacol. Immunotoxicol. 1999 Feb; 21(1): 109-24.
Williams, L., et al. “Immunomodulatory activities of Petiveria alliaceae L.” Phytother. Res. 1997; 11(3): 251253.
Rossi, V., “Effects of Petiveria alliacea L. on cell immunity.” Pharmacol. Res. 1993; 27(1): 111-12.
Marini, S., “Effects of Petiveria alliacea L. on cytokine production and natural killer cell activity.” Pharmacol. Res. 1993; 27(1): 107-08.
Anti-inflammatory & Pain-Relieving Actions:
Gomes, P. B., et al. “Study of antinociceptive effect of isolated fractions from Petiveria alliacea L. (tipi) in mice.” Biol. Pharm. Bull. 2005; 28(1): 42-6.
Lopes-Martins, R. A., et al. “The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (Phytolaccaceae).” Phytomedicine. 2002; 9(3): 245-48.
Dunstan, C. A., et al. “Evaluation of some Samoan and Peruvian medicinal plants by prostaglandin biosynthesis and rat ear oedema assays.” J. Ethnopharmacol. 1997 Jun; 57(1): 35-56.
Germano, D., et al. “Pharmacological assay of Petiveria alliaceae. Oral anti-inflammatory activity and gastrotoxicity of a hydro alcoholic root extract.” Fitoterapia. 1993; 64(5): 459-467.
Germano, D. H., et al. “Topical anti-inflammatory activity and toxicity of Petiveria alliaceae.” Fitoterapia. 1993; 64(5): 459-67.
de Lima, T. C., et al. “Evaluation of antinociceptive effect of Petiveria alliacea (Guine) in animals.” Mem. Inst. Oswaldo Cruz. 1991; 86 Suppl 2: 153-58.
Di Stasi, L. C., et al. “Screening in mice of some medicinal plants used for analgesic purposes in the state of Saõ Paulo.” J. Ethnopharmacol. 1988; 24(2/3): 205–11.
Antimicrobial & Antiparasitic Actions:
Kim, S., et al. “Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.” J. Ethnopharmacol. 2006 Mar; 104(1-2): 188-92.
Kubec, R., et al. “The lachrymatory principle of Petiveria alliacea.” Phytochemistry. 2003 May; 63(1): 37-40.
Ruffa, M. J., et al. “Antiviral activity of Petiveria alliacea against the bovine diarrhea virus. Chemotherapy 2002; 48(3): 144-47.
Benevides, P. J., et al. “Antifungal polysulphides from Petiveria alliacea L.” Phytochemistry. 2001; 57(5): 743-7.
Caceres, A., et al. “Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American trypanosomes of 13 native plants.” J. Ethnopharmacol. 1998 Oct; 62(3): 195-202.
Berger, I., et al. “Plants used in Guatemala for the treatment of protozoal infections: II. Activity of extracts and fractions of five Guatemalan plants against Trypanosoma cruzi.” J. Ethnopharmacol. 1998 Sep; 62(2): 107-15.
Hoyos, L., et al. “Evaluation of the genotoxic effects of a folk medicine, Petiveria alliaceae (Anamu).” Mutat. Res. 1992; 280(1): 29-34.
Caceres, A., et al. “Plants used in Guatemala for the treatment of dermatophytic infections. I. Screening for antimycotic activity of 44 plant extracts.” J. Ethnopharmacol. 1991; 31(3): 263-76.
Misas, C.A.J., et al. “The biological assessment of Cuban plants. III.” Rev. Cub. Med. Trop. 1979; 31(1): 21–27.
Von Szczepanski, C., et al. “Isolation, structure elucidation and synthesis of an antimicrobial substance from Petiveria alliacea.” Arzneim-Forsch 1972; 22: 1975–.
Feng, P., et al. “Further pharmacological screening of some West Indian medicinal plants.” J. Pharm. Pharmacol. 1964; 16: 115.
Hypoglycemic Actions:
Lans, C. A. "Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus." J. Ethnobiol. Ethnomedicine. 2006 Oct 13; 2: 45.
Lores, R. I., et al. “Petiveria alliaceae L. (anamu). Study of the hypoglycemic effect.” Med. Interne. 1990; 28(4): 347–52.
WARNINGS: Information, statements and products on this website have not been evaluated by the FDA and are not intended to diagnose, mitigate, treat, cure, or prevent any disease or health condition. The natural properties of the botanicals are only referred to their common uses among folk and herbal traditions. Our products are not intended to diagnose, cure, or prevent any disease as well. It's not meant to give any suggestion of diagnosis or disesase treatment. Please see a doctor when needed.