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Ingredients: 100% pure tamamuri bark (Brosimum acutifolium) extracted in distilled water and vegetable glycerine. No chemical additives or preservatives are used.
Suggested Use: As dietary supplement, take 60 drops 2-3 times daily or as needed.
Contraindications: None known.
Drug Interactions: None known.
Also Suggested:
- Guacatonga, from the Amazon an herb used as folk remedy for stomach disorders (ulcers, acid reflux, indigestion, dyspepsia, stomachache), skin rashes and wounds, and to purify the blood
- Simarouba, a Rainforest botanical used as a folk remedy against ulcers and internal bleeding
- Digestion Support, a proprietary blend of 7 rainforest botanical traditionally used for digestive disorders (acid reflux, gastric ulcers, etc.) and to support digestive functions
- Bowel Support, from the Amazon a blend of 7 plants used as folk remedies for colitis, IBS, constipation, and other bowel disorders
References on Tamamuri
Anti-inflammatory and PKC Inhibitory Actions:
Dos Santos, M. C., et al. "Avaliação do tratamento da artrite induzida por adjuvante completo de freund em ratos Lewis com as frações isoladas de Brosimum acutifolium." Proceedings of the XV Congresso de Iniciação Científica da UFAM. Brazil. Aug. 2003; page 223.
Dos Santos, M. C., et al. "Avaliação da toxicidade do extrato hidro-alcoólico e das frações isoladas de Brosimum acutifolium no tratamento da artrite induzida por adjuvante completo de freund em ratos Lewis." Proceedings of the XV Congresso de Iniciação Científica da UFAM. Brazil. Aug. 2003; page 222.
Takashima, J., et al. "Mururins A-C, three new lignoids from Brosimum acutifolium and their protein kinase inhibitory activity." Planta Med. 2002; 68(7): 621-625.
Aksoy, E., et al. "Protein kinase C epsilon: A new target to control inflammation and immune-mediated disorders." Int. J. Biochem. Cell Biol. 2004; 36(2): 183-8.
Cytotoxic & Antitumor Actions:
Stallings-Mann, M., et al. "A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells." Cancer Res. 2006 Feb; 66(3):1767-74.
Cohen, E. E., et al. "Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase." Cancer Res. 2006 Jun; 66(12): 6296-303.
Monks, N. R., et al. "Anti-tumour screening of Brazilian plants." Pharma. Biol. 2002; 40(8): 603–616.
Takashima, J., et al. "Brosimacutins J-M, four new flavonoids from Brosimum acutifolium and their cytotoxic activity." Planta Med. 2005; 71(7): 654-8.
Antimicrobial Actions:
Herforth, A., et al. "Amazonian Women's Medicine: Treatments for Mycoses." Poster: Society for Economic Botany 2002 vol 56(4).
Herforth, A., et al. " Antifungal plants of the Peruvian Amazon: A survey of ethnomedical uses and biological activity." Cornel University Publication 2002
Chemicals Identified:
Torres, S. L., et al. "Two flavans from Brosimum acutifolium." Phytochemistry. 1997; 44(2): 347-349.
Ferrari, F., et al. "(-)-epicatechin 5-o-beta-d-xylopyranoside from Brosimopsis acutifolium." Phytochemistry. 1998; 47(6): 1165-1166.
Torres, S. L., et al. "Flavonoids from Brosimum acutifolium." Phytochemistry. 2000; 53(8): 1047-1050.
Teixeira, A. F., et al. "Structure determination by H and C NMR of a new flavan isolated from Brosimum acutifolium: 4',7-dihydroxy-8-prenylflavan." Magn. Reson. Chem. 2000: 38(4): 301-304.
Takashima, J., et al. "Acutifolins A-F, a new flavan-derived constituent and five new flavans from Brosimum acutifolium." J. Nat. Prod. 2001: 64(12): 1493-1496.
Takashima, J., et al. Brosimacutins A-I, nine new flavonoids from Brosimum acutifolium." J. Nat. Prod. 2002; 65(12): 1843-1847.
WARNINGS: Information, statements and products on this website have not been evaluated by the FDA and are not intended to diagnose, mitigate, treat, cure, or prevent any disease or health condition. The natural properties of the botanicals are only referred to their common uses among folk and herbal traditions. Our products are not intended to diagnose, cure, or prevent any disease as well. It's not meant to give any suggestion of diagnosis or disesase treatment. Please see a doctor when needed.