Bellaco-caspi extract has been used for centuires by Indians as a wound healer and broad spectrum antimicrobial (bacteria, fungi, candida); for tumors and cancer; for lymphatic cleansing, inflammation, and infections; for endometriosis, uterine fibroid tumors, menstrual irregularities and pain, ovarian cysts and ovarian inflammation; as an anti-inflammatory and analgesic for arthritis, back pain, and muscle injury.
Ingredients: 100% pure bellaco-caspi bark and resin (Himatanthus sucuuba) extracted in distilled water and ethanol. No binders, fillers or additives are used.
Suggested Use: As dietary supplement, take 60 drops (2ml) 2- 3 times daily. It can be also used topically on the skin as desired.
MAO-Inhibition Actions:
Endo, Y. et al. "Confluentic acid and 2'-o-methylperlatolic acid, Monoamine Oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba." Chem. Pharm. Bull. 1994; 42(6): 1198-1201.
Anti-ulcerous Actions:
Baggio, C., et al. "Gastroprotective mechanisms of indole alkaloids from Himatanthus lancifolius." Planta Med. 2005; 71(8): 733-8.
Anti-inflammatory, Pain-relieving and Wound Healing Actions:
Villegas, L., et al. "Evaluation of the wound-healing activity of selected traditional medicinal plants from Peru." J. Ethnopharmacol. 1997; 55: 193-200.
De Miranda, A. L., et al. "Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba." Planta Med. 2000; 66(3): 284-286.
Anti-spasmodic Actions:
Rattmann, Y. et al. "Effects of alkaloids of Himatanthus lancifolius (Muell. Arg.) Woodson, Apocynaceae, on smooth muscle responsiveness." J. Ethnopharmacol. 2005 Sep; 100(3): 268-75.
Anti-tumor & Cytotoxic Actions:
Guignard, E., et al. "Screening of plants found in Amazonas state for lethality towards brine shrimp." Acta Amazonica. 2003; 33(1): 93-104.
Bolzani, V., et al. "Search for antifungal and anticancer compounds from native plant species of cerrado and Atlantic Forest." An. Acad. Bras. Cienc. 1999; 71(2): 181-7.
Persinos-Perdue, G., et al. " South American plants. III. Isolation of fulvoplumierin from Himatanthus sucuuba (Apocynaceae). J. Pharm. Sci. 1978; 67: 1322.
Kardono, L., et al. "Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia." J. Nat. Prod. 1990 Nov-Dec; 53(6):1447-55.
Wood, C. A., et al. "A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba." Chem. Pharm. Bull. 2001; 49(11): 1477-1478.
De Silva, J. R., et al. "Triterpenic esters from Himatanthus sucuuba (Spruce) Woodson." Quimica Nova 1998; 21(6): 702-704.
Abdel-Kader, M., et al. "Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest." J. Nat. Prod. 1997; 60(12): 1294-7.
Hamburger, M., et al. "Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra." J. Ethnopharmacol. 1991 Jul; 33(3): 289-92.
Antimicrobial Actions:
Moreira, D., et al. "Actividades antimicrobiologicas dos stratos e fracoes obtido atraves de solventes organicos da casca da Himatanthus sucuuba do vale do Acre." Anais Do XV Seminario De Iniciacao Cientifica PIBIQ-CNPQ, 2006: Universidade Federal Do Acre, Rio Branco-Acre, Brazil.
Souza, W., et al. "Antimicrobial activity of alkaloidal fraction from barks of Himatanthus lancifolius." Fitoterapia. 2004 Dec; 75(7-8): 750-3.
Little, J., et al. "Plumericin; an antimicrobial agent from Plumeria multiflora." Arch. Biochem. 1951; 30(2): 445-52.
Persinos-Perdue, G., et al. " South American plants. III. Isolation of fulvoplumierin from Himatanthus sucuuba (Apocynaceae). J. Pharm. Sci. 1978; 67: 1322.
Wood, C. A., et al. "A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba." Chem. Pharm. Bull. 2001; 49(11): 1477-1478.
De Silva, J. R., et al. "Triterpenic esters from Himatanthus sucuuba (Spruce) Woodson." Quimica Nova 1998; 21(6): 702-704.
Abdel-Kader, M., et al. "Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest." J. Nat. Prod. 1997; 60(12): 1294-7.
Hamburger, M., et al. "Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra." J. Ethnopharmacol. 1991 Jul; 33(3): 289-92.
Kardono, L., et al. "Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia." J. Nat. Prod. 1990 Nov-Dec; 53(6):1447-55.
Jovel, E., et al. "An ethnobotanical study of the traditional medicine of the Mestizo people of Suni Mirano, Loreto, Peru." J. Ethnopharmacol. 1996; (53): 149-156.
Bolzani, V., et al. "Search for antifungal and anticancer compounds from native plant species of cerrado and Atlantic Forest." An. Acad. Bras. Cienc. 1999; 71(2): 181-7.
Toxicity Studies:
De Oliveira Guerra, M., et al. "Screening for reproductive toxicity in rats for a decoction of Himathanthus sucuuba stem bark." J. Ethnopharmacol. 1991; 34(2/3): 195-199.
WARNINGS: Information, statements and products on this website have not been evaluated by the FDA and are not intended to diagnose, mitigate, treat, cure, or prevent any disease or health condition. The natural properties of the botanicals are only referred to their common uses among folk and herbal traditions. Our products are not intended to diagnose, cure, or prevent any disease as well. It's not meant to give any suggestion of diagnosis or disesase treatment. Please see a doctor when needed.