Estriol

The body naturally makes three estrogen hormones: estradiol, estrone, and estriol.

Estriol is produced in high levels during pregnancy by the placenta. When a woman is not pregnant, estriol is naturally produced in small amounts in the body.

Estriol is the ''weakest'' of the estrogens, but studies show that estriol's weakness may also be its strength.
Since its estrogenic activity is weaker than estrone and estradiol, it has little or no side effects when used in low doses.

Several clinical trials have reported that estriol could help coping with menopausal symptoms and aging process without the dangerous side effects that studies have linked to synthetic estrone and estradiol.

Clinical trials and studies performed through the years have documented that estriol might be helpful in:

• relieving menopausal symptoms such as hot flashes, and insomnia
• preventing bone loss
• reducing vaginal dryness and promoting urinary tract health in menopausal and postmenopausal women
• reducing markers of cardiovascular risk
• improving skin appearance and reducing fine lines and wrinkles.

References
Altern Med Rev. 1998 Apr;3(2):101-13
Franks O.A.M, ND& Wright J.V., MD, Estriol: Its Weakness is Its Strenght, Life Extension 08/2008
The Most popular Drug In The Country, Life Extension Magazine, January 1996
Preventing Bone Loss, Life Extension Magazine, January 1996
Estrogen Therapy? Don't Worry!, Life Extension Magazine, October 1999
Estriol: The Friendly Estrogen, Woman's Health.com
Head KA, Estriol: Safety and Efficay, Alternative medicine review, 1998 Apr;3(2):101-13.
JB, Binder M, Demschik G, Bieglmayer C, Reiner A., Treatment of skin aging with topical estrogens, International Journal of Dermatology, 1996 Sep;35(9):669-74.













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