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Bowel Support (intestino)

Bowel Support (intestino)
120 Caps (650mg)
29.90€
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Bowel Support combina 7 piante della foresta pluviale usate dagli sciamani del Sud America come rimedi popolari per coliti, sindrome dell'intestino irritabile, costipazione cronica, diverticolite e colite ulcerosa. Bowel Support può essere utilizzato come integratore alimentare coadiuvante per supportare la funzionalità intestinale.


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Ingredienti: 100% pura miscela di cat's claw, macela, boldo, simarouba, jurubeba, tayuya e anamu. Non sono stati usati leganti, riempitivi o altri additivi.

Uso suggerito: Come integratore alimentare. Prendere 2-3 capsule 3 volte al giorno a stomaco vuoto.

Controindicazioni:
  • Non usare durante la gravidanza o l'allattamento.
  • Si sconsiglia l'uso di questo prodotto assieme agli immunosoppressivi.

Interazioni con farmaci:
  • Può potenziare gli anticoagulanti.
  • Può ridurre l'effetto degli immunosoppressivi.

Altre indicazioni pratiche:
  • Numerose piante in questa formulazione contengono una bassa concentrazione di cumarina che ha effetti anticoagulanti. Chi soffre di disturbi del sangue come l'emofilia o chi assume anticoagulanti dovrebbe monitorarsi per questo possibile effetto.
  • Cat's claw e jurubeba hanno degli effetti anti-fertilità documentati. Chi è alla ricerca di una gravidanza o chi è sottoposto ad un trattamento contro la sterilità dovrebbe evitare l'uso di questa formulazione.
Precauzioni: Non superare la dose giornaliera raccomandata. Questo prodotto è un supplemento nutrizionale che non deve sostituire un’alimentazione varia ed equilibrata. Tenere lontano dalla portata dei bambini al di sotto dei 3 anni. Conservare al riparo dalla luce, da fonti di calore e dall’umidità. Come con ogni supplemento nutrizionale, consultare un medico prima di assumerlo durante la gravidanza, l’allattamento o nel caso di problemi di salute.

Bibliografia

Cat's Claw (Uncaria tomentosa)
Hardin, S. R. "Cat's claw: An Amazonian vine decreases inflammation in osteoarthritis." Complement. Ther. Clin. Pract. 2007 Feb; 13(1): 25-8.
Allen-Hall, L., et al. "Treatment of THP-1 cells with Uncaria tomentosa extracts differentially regulates the expression if IL-1beta and TNF-alpha." J. Ethnopharmacol. 2007 Jan; 109(2): 312-7.
Miller, M. J., et al. "The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta." BMC Complement. Altern. Med. 2006 Apr; 6: 13.
Miller, M. J., et al. "Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: a randomized controlled trial [ISRCTN38432711]." J. Inflamm. 2005 Oct; 2:11.
Valerio, L. G., et al. "Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii): a critical synopsis." Toxicol. Rev. 2005; 24(1): 11-35.
Setty, A. R., et al. "Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects." Semin. Arthritis Rheum. 2005; 34(6): 773-84.
Sheng, Y., et al. “An active ingredient of Cat's Claw water extracts: identification and efficacy of quinic acid.” J. Ethnopharmacol. 2005 Jan 15; 96(3):
Aguilar, J. L., et al. “Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae).” J. Ethnopharmacol. 2002; 81(2): 271–76.
Sandoval, M., et al., “Anti-inflammatory and antioxidant activities of cat’s claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content." Phytomedicine. 2002; 9(4): 325–37.
Mur, E., et al. “Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis.” J. Rheumatol. 2002 Apr; 29(4): 678–81.
Sandoval-Chacon, M., et al. “Anti-inflammatory actions of cat’s claw: the role of NF-kappaB.” Aliment. Pharmacol. Ther. 1998; 12(12): 1279–89.
Recio, M. C., et al. “Structural requirements for the anti-inflammatory activity of natural triterpenoids.” Planta Med. 1995; 61(2): 182–85.
Aquino, R., et al. “Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa." J. Nat. Prod. 1991; 54: 453–59.
Cerri, R., et al. “New quinovic acid glycosides from Uncaria tomentosa." J. Nat. Prod. 1988; 51: 257–61.

Boldo (Peumus boldus)
Gotteland, M., et al. “Protective effect of boldine in experimental colitis.” Planta Med. 1997; 63(4): 311–15.
Gotteland, M., et al. “Effect of a dry boldo extract on oro-cecal intestinal transit in healthy volunteers.” Rev. Med. Chil. 1995; 123(8): 955–60.
Estelles, R., et al. “Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neurtrophil recruitment in vivo.” J. Leukoc. Biol. 2005 Sep; 78(3): 696-704.
Kang, J. J., et al. “Studies on neuromuscular blockade by boldine in the mouse phrenic nerve diaphragm.” Planta Med. 1999; 65(2): 178–79.
Kang, J. J., et al. “Effects of boldine on mouse diaphragm and sarcoplasmic reticulum vesicles isolated from skeletal muscle.” Planta Med. 1998; 64(1): 18–21.
Backhouse, N., et al. “Anti-inflammatory and antipyretic effects of boldine.” Agents Actions 1994; 42(3–4): 114–17.
Ivorra, M. D., et al. “Different mechanism of relaxation induced by aporphine alkaloids in rat uterus.” J. Pharm. Pharmacol. 1993; 45(5): 439–43.
Lanhers, M. C., et al. “Hepatoprotective and anti-inflammatory effects of a traditional medicinal plant of Chile, Peumus boldus.” Planta Med. 1991; 57(2): 110–15.
O'brien, P., et al. “Boldine and its antioxidant or health-promoting properties.” Chem. Biol. Interact. 2006 Jan; 159(1): 1-17.

Macela (Achyrocline satureoides, Egletes viscosa)
Rao, V. S., et al. “Investigations on the gastroprotective and antidiarrhoeal properties of ternatin, a tetramethoxyflavone from Egletes viscosa.” Planta Med. 1997 Apr; 63(2): 146-9.
Lima, M. A., et al. ”Biologically active flavonoids and terpenoids from Egletes viscosa.” Phytochemistry. 1996; 41(1): 217-23.
Rao, V. S., et al. “Protective effect of ternatin, a flavonoid isolated from Egletes viscosa Less., in experimental liver injury.”
Pharmacology. 1994; 48(6): 392-7.
Melo, C. M., et al. "12-Acetoxyhawtriwaic acid lactone, a diterpene from Egletes viscosa, attenuates capsaicin-induced ear edema and hindpaw nociception in mice: possible mechanisms." Planta Med. 2006 Jun; 72(7): 584-9.
Hnatyszyn, O., et al. “Flavonoids from Achyrocline satureioides with relaxant effects on the smooth muscle of guinea pig corpus cavernosum.” Phytomedicine. 2004; 11(4): 366-9.
Rao. V. S., et al. “Ternatin, an anti-inflammatory flavonoid, inhibits thioglycolate-elicited rat peritoneal neutrophil accumulation and LPS-activated nitric oxide production in murine macrophages.” Planta Med. 2003; 69(9): 851-3.
Guedes, M. M., et al. “Antinociceptive and gastroprotective effects of diterpenes from the flower buds of Egletes viscosa.” Planta Med. 2002; 68(11): 1044-6.
Lima, M. A., et al. ”Biologically active flavonoids and terpenoids from Egletes viscosa.” Phytochemistry. 1996; 41(1): 217-23.
Souza, M. F., et al. “Anti-anaphylactic and anti-inflammatory effects of ternatin, a flavonoid isolated from Egletes viscosa Less.” Braz. J. Med. Biol. Res. 1992; 25(10): 1029-32.
Simoes, C. M., “Anti-inflammatory action of Achyrocline satureoides extracts applied topically.” Fitoterapia. 1988; 59(5): 419–21.
Simoes, C. M., et al. “Pharmacological investigations on Achyrocline satureoides (Lam). D.C., Compositae.” J. Ethnopharmacol. 1988 Apr; 22(3): 281–93.
Polydoro, M., et al. “Antioxidant, a pro-oxidant and cytotoxic effects of Achyrocline satureioides extracts.” Life Sci. 2004 Apr; 74(23): 2815-26.
Vieira, M. M., et al. “Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats.” Phytother. Res. 2004; 18(2): 135-41.
Gugliucci, A., et al. “Three different pathways for human LDL oxidation are inhibited in vitro by water extracts of the medicinal herb Achyrocline satureoides.” Life Sci. 2002; 71(6): 693–705.
Kadarian, C., et al. “Hepatoprotective activity of Achyrocline satureioides (Lam.) D.C.” Pharmacol. Res. 2002; 45(1): 57–61.
Souza, M.F., et al. “Inhibition by the bioflavonoid ternatin of aflatoxin B1-induced lipid peroxidation in rat liver.” J. Pharm. Pharmacol. 1999; 51(2):125-9.
Desmarchelier, C., et al. “Antioxidant and free radical scavenging effects in extracts of the medicinal herb Achyrocline satureioides (Lam.) D.C. (marcela).” Braz. J. Med. Biol. Res. 1998; 31(9): 163–70.
Desmarchelier, C., et al. “Antioxidant and prooxidant activities in aqueous extracts of Argentine Plants.” Int. J. Pharmacog. 1997; 35(2): 116–20.

Simarouba (Simarouba amara)
Caceres, A. “Plants used in Guatemala for the treatment of gastrointestinal disorders. 1. Screening of 84 plants against enterobacteria." J. Ethnopharmacol. 1990; 30(1): 55–73.
Wright, C. W. “Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids.” Antimicrob. Agents Chemother. 1988; 32(11): 1725-1729.
Wright, C. W., et al. “Quassinoids exhibit greater selectivity against Plasmodium falciparum than against Entamoeba histolytica, Giardia intestinalis or Toxoplasma gondii in vitro. J. Eukaryot. Microbiol. 1993 ; 40(3): 244-6.
Duriez, R., et al. “Glaucarubin in the treatment of amebiasis." Presse Med. 1962; 70: 1291.

Jurubeba (Solanum paniculatum)
Botion, L. M., et al. “Effects of the Brazilian phytopharmaceutical product jerobina® on lipid metabolism and intestinal tonus.” J. Ethnopharmacol. 2005 Nov; 102(2): 137-42.
Braga, F. T., et al. Jurubeba. Centro Universitário de Lavras, Lavras-MG Brazil, 2002.
Mesia-Vela, S., et al. “Solanum paniculatum L. (Jurubeba): Potent inhibitor of gastric acid secretion in mice.” Phytomedicine 2002; 9(6): 508–14.
Barros, G. S. G., et al. “Phamacological screening of some Brazilian plants.” J. Pharm. Pharmac. 1969; 22: 116–22.

Tayuya (Cayaponia tayuya)
Truiti, M.C., et al. “Antiprotozoal and molluscicidal activities of five Brazilian plants.” Braz. J. Med. Biol. Res. 2005; 38(12): 1873-8
Escandell, J. M., et al. “Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis.” Eur. J. Pharmacol. 2006 Feb; 532(1-2): 145-54.
Recio, M. C., et al. “Anti-inflammatory activity of two cucurbitacins isolated from Cayaponia tayuya roots.” Planta Med. 2004; 70(5): 414-20.
Himeno, E., et al. “Structures of cayaponosides A, B, C and D, glucosides of new nor-cucurbitacins in the roots of Cayaponia tayuya.” Chem. Pharm. Bull. (Tokyo) 1992; 40(10): 2885–87.
Ruppelt, B. M., et al. “Pharmacological screening of plants recommended by folk medicine as anti-snake venom—I. Analgesic and anti-inflammatory activities.” Mem. Inst. Oswaldo Cruz 1991; 86 (Suppl. 2): 203–5.
Rios, J. L., et al. “A study of the anti-inflammatory activity of Cayaponia tayuya root.” Fitoterapia 1990; 61(3):275–78.
Huguet, A. I., et al. “Superoxide scavenging properties of flavonoids in a non-enzymic system.” Z. Natur. Forsch. 1990; 45(1–2): 19–24.

Anamu (Petiveria alliacea)
Gomes, P. B., et al. “Study of antinociceptive effect of isolated fractions from Petiveria alliacea L. (tipi) in mice.” Biol. Pharm. Bull. 2005; 28(1): 42-6.
Lopes-Martins, R. A., et al. “The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (Phytolaccaceae).” Phytomedicine. 2002; 9(3): 245-48.
Dunstan, C. A., et al. “Evaluation of some Samoan and Peruvian medicinal plants by prostaglandin biosynthesis and rat ear oedema assays.” J. Ethnopharmacol. 1997 Jun; 57(1): 35-56.
Germano, D., et al. “Pharmacological assay of Petiveria alliaceae. Oral anti-inflammatory activity and gastrotoxicity of a hydro alcoholic root extract.” Fitoterapia. 1993; 64(5): 459-467.
Germano, D. H., et al. “Topical anti-inflammatory activity and toxicity of Petiveria alliaceae.” Fitoterapia. 1993; 64(5): 459-67.
de Lima, T. C., et al. “Evaluation of antinociceptive effect of Petiveria alliacea (Guine) in animals.” Mem. Inst. Oswaldo Cruz. 1991; 86 Suppl 2: 153-58.
Di Stasi, L. C., et al. “Screening in mice of some medicinal plants used for analgesic purposes in the state of Saõ Paulo.” J. Ethnopharmacol. 1988; 24(2/3): 205–11.
Kim, S., et al. “Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.” J. Ethnopharmacol. 2005 Oct 13;
Ruffa, M. J., et al. “Antiviral activity of Petiveria alliacea against the bovine diarrhea virus. Chemotherapy 2002; 48(3): 144-47.
Caceres, A., et al. “Plants used in Guatemala for the treatment of protozoal infections. I. Screening of activity to bacteria, fungi and American trypanosomes of 13 native plants.” J. Ethnopharmacol. 1998 Oct; 62(3): 195-202.
Berger, I., et al. “Plants used in Guatemala for the treatment of protozoal infections: II. Activity of extracts and fractions of five Guatemalan plants against Trypanosoma cruzi.” J. Ethnopharmacol. 1998 Sep; 62(2): 107-15.
Von Szczepanski, C., et al. “Isolation, structure elucidation and synthesis of an antimicrobial substance from Petiveria alliacea.” Arzneim-Forsch 1972; 22: 1975–.



















AVVERTENZA: Le informazioni fornite in queste pagine hanno solo scopo informativo e sono tratte da pubblicazioni internazionali. Le proprietà naturali delle erbe sono unicamente da riferire alle comuni utilizzazioni nella tradizione popolare ed erboristica. I nostri prodotti non si propongono di diagnosticare, trattare, curare o prevenire alcuna malattia. Non si intende fornire suggerimenti per diagnosi o trattamenti di malattie. In caso di necessità consultare un medico.