argento colloidale ionico (colloidal silver) *hef biotensor candida albicans chanca piedra *hef cmo plus e sea plus kit convenienza cortisolo (regolazione) disfunzioni ghiandole surrenali estrogeni graviola *hef graviola max *hef huanarpo macho extract *hef leucemia: integrazione coadiuvante e prevenzione malattie autoimmuni msm glucosamina condroitina *hef n-tense *hef perchè i prodotti naturvitae sono i più potenti? progestacare -natural progesterone *hef progesterone naturale prostata-ingrossamento yerba mate Tutti i tag
Che cosa significa "HEF"? Per scoprirlo, clicca qui.
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Ingredienti: 100% pura chanca piedra (Phyllanthus niruri). Non è stato aggiunto alcun eccipiente o additivo.
Uso suggerito: Come integratore alimentare. Prendere 2-3 capsule due volte al giorno.
Controindicazioni: Nessuna segnalata.
Interazioni con farmaci: Nessuna segnalata. Tuttavia, potrebbe potenziare gli effetti degli antipertensivi, dei diuretici e dei farmaci per il diabete.
Altre indicazioni pratiche:
- Alcuni studi hanno evidenziato che Chanca piedra può ridurre la pressione arteriosa. Si consiglia perciò agli individui che soffrono di ipotensione un monitoraggio costante
- E' emerso da alcuni test di laboratorio che Chanca piedra potrebbe avere effetti negativi sulla fertilità delle donne. L'assunzione non è perciò consigliabile alle donne alla ricerca di una gravidanza.
- Chanca piedra ha dimostrato in alcuni test una possibile attività ipoglicemica. Gli individui che soffrono di ipoglicemia dovrebbero pertanto sottoporsi ad un monitoraggio costante.
- Caigua, coadiuvante per i disturbi legati al colesterolo alto e circolatori
- Pata de vaca, coadiuvante per i disturbi renali e urinari (viene utilizzata dalla medicina popolare come diuretico), oltre che per il diabete
- Heart Support, miscela di erbe utilizzate dalla medicina popolare per i disturbi legati alla circolazione
- Carqueja Concentrated Extract, estratto dall'omonima pianta che viene utilizzata in Brasile come rimedio popolare per i disturbi della cistifellea
Bibliografia su Chanca piedra
Sulle azioni sui calcoli renali e l'acido urico:
Murugaiyah V, et al. "Antihyperuricemic lignans from the leaves of Phyllanthus niruri." Planta Med. 2006 Nov; 72(14): 1262-7.
Micali, S., et al. "Can Phyllanthus niruri affect the efficacy of extracorporeal shock wave lithotripsy for renal stones? A randomized, prospective, long-term study." J. Urol. 2006 Sep; 176(3): 1020-2.
Barros, M. E., et al. "Effect of extract of Phyllanthus niruri on crystal deposition in experimental urolithiasis." Urol. Res. 2006 Aug 1;
Nishiura, J. L., et al. “Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.” Urol. Res. 2004 Oct; 32(5): 362-6.
Barros, M. E., et al. “Effects of an aqueous extract from Phyllanthus niruri on calcium oxalate crystallization in vitro.” Urol. Res. 2003; 30(6): 374-9.
Freitas, A. M., et al. “The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation.” B. J. U. Int. 2002; 89(9): 829–34.
Campos, A. H., et al. “Phyllanthus niruri inhibits calcium oxalate endocytosis by renal tubular cells: its role in urolithiasis.” Nephron. 1999; 81(4): 393–97.
Sulle azioni antispasmodiche, antidolorifiche e antinfiammatorie:
Kassuya, C. A., et al. "Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor." Eur. J. Pharmacol. 2006 Sep; 546(1-3): 182-8.
Iizuka, T., et al. “Vasorelaxant Effects of Methyl Brevifolincarboxylate from the Leaves of Phyllanthus niruri.” Biol. Pharm. Bull. 2006; 29(1): 177-9.
Kassuya, C.A., et al. “Anti-inflammatory properties of extracts, fractions and lignans isolated from Phyllanthus amarus.” Planta Med. 2005; 71(8): 721-6.
Kiemer, A. K., et al. “Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway.” J. Hepatol. 2003; 38(3): 289-97.
Santos, A. R., et al. “Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae).” J. Ethnopharmacol. 2000; 72(1/2): 229–38.
Miguel, O. G., et al. “Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus.” Planta Med. 1996; 62(2): 146–49.
Santos, A. R., et al. “Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.” Gen. Pharmacol. 1995; 26(7): 1499–1506.
Santos, A. R., et al. “Further studies on the antinociceptive action of the hydroalcohlic extracts from plants of the genus Phyllanthus.” J. Pharm. Pharmacol. 1995; 47(1): 66–71.
Santos, A. R., et al. “Analgesic effects of callus culture extracts from selected species of Phyllanthus in mice.” J. Pharm. Pharmacol. 1994; 46(9): 755–59.
Sulle azioni antivirali:
Huang, R. L., et al. “Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro.” Phytother. Res. 2003; 17(5): 449-53.
Liu, J., et al. “Genus Phyllanthus for chronic Hepatitis B virus infection: A systematic review.” Viral Hepat. 2001; 8(5): 358–66.
Xin-Hua, W., et al. “A comparative study of Phyllanthus amarus compound and interferon in the treatment of chronic viral Hepatitis B.” Southeast Asian J. Trop. Med. Public Health 2001; 32(1): 140–42.
Wang, M. X., et al. “Herbs of the genus Phyllanthus in the treatment of chronic Hepatitis B: Observation with three preparations from different geographic sites.” J. Lab. Clin. Med. 1995; 126(4): 350–52.
Wang, M. X., et al. “Observations of the efficacy of Phyllanthus spp. in treating patients with chronic Hepatitis B.” 1994; 19(12): 750–52.
Thyagarajan, S. P., et al. “Effect of Phyllanthus amarus on chronic carriers of Hepatitis B virus.” Lancet 1988; 2(8614): 764–66.
Venkateswaran, P. S., et al. “Effects of an extract from Phyllanthus niruri on Hepatitis B and wood chuck hepatitis viruses: in vitro and in vivo studies.” Proc. Nat. Acad. Sci. 1987; 84(1): 274–78.
Bhumyamalaki, et al. “Phyllanthus niruri and jaundice in children.” J. Natl. Integ. Med. Ass. 1983; 25(8): 269–72.
Thyagarajan, S. P., et al. “In vitro inactivation of HBsAG by Eclipta alba (Hassk.) and Phyllanthus niruri (Linn.).” Indian J. Med. Res. 1982; 76s: 124–30.
Notka, F., et al. “Concerted inhibitory activities of Phyllanthus amarus on HIV replication in vitro and ex vivo.” Antiviral Res. 2004 Nov; 64(2): 93-102.
Notka, F., et al. “Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus.” Antiviral Res. 2003 Apr; 58(2): 175-186.
Qian-Cutrone, J. “Niruriside, a new HIV REV/RRE binding inhibitor from Phyllanthus niruri.” J. Nat. Prod. 1996; 59(2): 196–99.
Ogata, T., et al. “HIV-1 reverse transcriptase inhibitor from Phyllanthus niruri.” AIDS Res. Hum. Retroviruses 1992; 8(11): 1937–44.
Sulle azioni di protezione e disintossicazione del fegato:
Bhattacharjee, R., et al. "Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties." Food Chem. Toxicol. 2006 Nov 11;
Chatterjee, M., et al. "Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo." Indian J. Biochem. Biophys. 2006 Oct; 43(5): 299-305.
Bhattacharjee, R., et al. "The protein fraction of Phyllanthus niruri plays a protective role against acetaminophen induced hepatic disorder via its antioxidant properties." Phytother. Res. 2006; 20(7): 595-601.
Lee, C. Y., et al. "Hepatoprotective effect of Phyllanthus in Taiwan on acute liver damage induced by carbon tetrachloride." Am. J. Chin. Med. 2006; 34(3): 471-82.
Chatterjee, M., et al. "Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress." Pathophysiology. 2006 May; 13(2): 95-102.
Khatoon, S., et al. “Comparative pharmacognostic studies of three Phyllanthus species.” 2006 Mar; 104(1-2): 79-86.
Levy, C., et al. “Use of herbal supplements for chronic liver disease.” Clin. Gastroenterol Hepatol. 2004; 2(11): 947-56.
Rajeshkumar, N. V., et al. “Phyllanthus amarus extract administration increases the life span of rats with hepatocellular carcinoma.” J. Ethnopharmacol. 2000 Nov; 73(1–2): 215–19.
Padma, P., et al. "Protective effect of Phyllanthus fraternus against carbon tetrachloride-induced mitochondrial dysfunction." Life Sci. 1999; 64(25): 2411-17.
Jeena, K. J., et al. “Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on n-nitrosodiethylamine induced hepatocarcinogenesis.” Cancer Lett. 1999; 136(1): 11–16.
Thabrew, M. R., et al. “Phytogenic agents in the therapy of liver disease.” Phytother. Res. 1996; 10(6): 461–67.
Prakash, A., et al. “Comparative hepatoprotective activity of three Phyllanthus species, P. urinaria, P. niruri and P.simplex, on carbon tetrachloride induced liver injury in the rat.” Phytother. Res. 1995; 9(8): 594–96.
Dhir, H., et al. “Protection afforded by aqueous extracts of Phyllanthus species against cytotoxicity induced by lead and aluminium salts.” Phytother. Res. 1990; 4(5): 172–76
Sreenivasa, R. Y. “Experimental production of liver damage and its protection with Phyllanthus niruri and Capparis spinosa (both ingredients of LIV52) in white albino rats.” Probe 1985; 24(2): 117–19.
Syamasundar, K. V., et al. "Antihepatotoxic principles of Phyllanthus niruri herbs." J. Ethnopharmacol. 1985; 14(1): 41-4.
Sulle azioni anticancro e di protezione cellulare:
Leite, D. F., et al. "The cytotoxic effect and the multidrug resistance reversing action of lignans from Phyllanthus amarus." Planta Med. 2006 Dec; 72(15): 1353-8.
Raphael, K. R., et al. "Inhibition of N-Methyl N'-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis by Phyllanthus amarus extract." Asian Pac. J. Cancer Prev. 2006 Apr-Jun; 7(2): 299-302.
Hari Kumar, K. B., et al . "Inhibition of drug metabolizing enzymes (cytochrome P450) in vitro as well as in vivo by Phyllanthus amarus Schum & Thonn." Biol. Pharm. Bull. 2006; 29(7): 1310-3.
Mellinger, C. G., et al. “Chemical and biological properties of an arabinogalactan from Phyllanthus niruri.” J. Nat. Prod. 2005; 68(10): 1479-83.
Kumar, K. B., et al. “Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice.” Phytomedicine. 2005; 12(6-7): 494-500.
Raphael, K. R., et al. “Inhibition of experimental gastric lesion and inflammation by Phyllanthus amarus extract.” J. Ethnopharmacol. 2003; 87(2-3): 193-7.
Rajeshkumar, N. V. "Antitumour and anticarcinogenic activity of Phyllanthus amarus extract." J. Ethnopharmacol. 2002; 81(1): 17-22.
Sripanidkulchai, B., et al. “Antimutagenic and anticarcinogenic effects of Phyllanthus amarus.” Phytomedicine 2002; 9(1): 26–32.
Devi, P. U. “Radioprotective effect of Phyllanthus niruri on mouse chromosomes.” Curr. Sci. 2000; 78(10): 1245–47.
Souza, C. R., et al. “Compounds extracted from Phyllanthus and Jatropha elliptica inhibit the binding of [3H]glutamate and [3H]GMP-PNP in rat cerebral cortex membrane.” Neurochem. Res. 2000; 25(2): 211–15.
Sulle azioni anti- diabete e anti- colesterolo:
Adeneye, A. A., et al. "Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice." Fitoterapia. 2006 Dec; 77(7-8): 511-4.
Ali, H., et al. "alpha-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus." J. Ethnopharmacol. 2006 Oct; 107(3): 449-55.
Raphael, K. R., et al. “Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential.” Indian J. Exp. Biol. 2002; 40(8): 905-9.
Khanna, A. K., et al. "Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats." J. Ethnopharmacol. 2002; 82(1): 19-22.
Srividya, N., et al. “Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus.” Indian J. Exp. Biol. 1995; 33(11): 861–64.
Shimizu, M., et al. “Studies on aldose reductase inhibitors from natural products. II. Active components of a Paraguayan crude drug, ‘paraparai mi,’ Phyllanthus niruri.” Chem. Pharm. Bull. (Tokyo) 1989; 37(9): 2531–32.
Umarani, D., et al. “Ethanol induced metabolic alterations and the effect of Phyllanthus niruri in their reversal.” Ancient Sci. Life 1985; 4(3): 174–80.
Ramakrishnan, P. N., et al. “Oral hypoglycaemic effect of Phyllanthus niruri (Linn.) leaves.” Indian J. Pharm. Sci. 1982; 44(1): 10–12.
Sulle azioni antiparassitarie, antimalariche, cicatrizzanti e antimicrobiche:
Mazumder, A., et al. "Antimicrobial potentiality of Phyllanthus amarus against drug resistant pathogens." Nat. Prod. Res. 2006; 20(4):323-6.
Devi, V., et al. "Effect of Phyllanthus niruri on wound healing in rats." Indian J. Physiol Pharmacol. 2005 Oct-Dec; 49(4): 487-90.
Kolodziej, H., et al. "Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells." Bioorg. Med. Chem. 2005 Dec; 13(23): 6470-6.
Subeki, S., et al. "Anti-babesial and anti-plasmodial compounds from Phyllanthus niruri." J. Nat. Prod. 2005; 68(4): 537-9.
Kloucek, P., et al. “Antibacterial screening of some Peruvian medicinal plants used in Calleria District.” J. Ethnopharmacol. 2005 Jun; 99(2): 309-12.
Cimanga, R. K., et al. “In vitro antiplasmodial activity of callus culture extracts and fractions from fresh apical stems of Phyllanthus niruri L. (Euphorbiaceae): part 2.” J. Ethnopharmacol. 2004 Dec; 95(2-3): 399-404.
Agrawal, A., et al. “Evaluation of inhibitory effect of the plant Phyllanthus amarus against dermatophytic fungi Microsporum gypseum.” Biomed. Environ. Sci. 2004 Sep; 17(3): 359-65.
Tona, L., et al. “In vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the Democratic Republic of Congo.” J. Ethnopharmacol. 2004 Jul; 93(1): 27-32.
Mesia, L. T. K., et al. “In-vitro antimalarial activity of Cassia occidentalis, Morinda morindoides and Phyllanthus niruri.” Ann. Trop. Med. Parasitol. 2001; 95(1): 47–57.
Tona, L., et al. “Antimalarial activity of 20 crude extracts from nine African medicinal plants used in Kinshasa, Congo.” J. Ethnopharmacol. 1999; 68(1/3): 193–203.
Farouk, A., et al. “Antimicrobial activity of certain Sudanese plants used in folkloric medicine. Screening for antibacterial activity (I).” Fitoterapia 1983; 54(1): 3–7.
AVVERTENZA: Le informazioni fornite in queste pagine hanno solo scopo informativo e sono tratte da pubblicazioni internazionali. Le proprietà naturali delle erbe sono unicamente da riferire alle comuni utilizzazioni nella tradizione popolare ed erboristica. I nostri prodotti non si propongono di diagnosticare, trattare, curare o prevenire alcuna malattia. Non si intende fornire suggerimenti per diagnosi o trattamenti di malattie. In caso di necessità consultare un medico.